The present invention is directed to a dual diameter guide wire that is steerable inside the lumen of a patient, and provides greater ability to access small areas such as the interior of a needle, or the interior of a patients lumen such as small blood vessels, thereby improving access to a patients body during interventional procedures. The present invention is also directed to medical devices for interventional applications, methods of accessing the interior of a lumen of a patients body and methods of preparing a guide wire.