CHEMIKALIEN UND VERFAHREN ZUR VERHINDERUNG UND BEHANDLUNG VON TGF-BETA-VERMITTELTER AKTIVIERUNG VON FIBROBLASTEN ZUR REDUZIERUNG UND BEHANDLUNG VON KREBS UND FIBROSE
Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
发明人:
CARDELLI, James Allen,STEPHENS, Charles Albert,GRAY, Alana Lea,COLEMAN, David Thomas
申请号：
EP17748126
公开号：
EP3411045A4
申请日:
2017.02.02
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
A method of treating an activated fibroblast associated disease or pre-disease condition in a mammal comprising, administering a pharmaceutical composition including a therapeutically effective amount of a first therapeutic, wherein the first therapeutic is one of an intracellular Ca2+ elevator, a YAP/TAZ inhibitor, both a intracellular Ca2+ elevator and a YAP/TAZ inhibitor, or pharmacologically acceptable salts, solvates, esters, amides, clathrates, stereoisomers, enantiomers, prodrugs or analogs thereof, or a combination thereof.
