Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them

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专利权人:

Santarus; Inc.

发明人:

Proehl, Gerald T.,Hall, Warren,Olmstead, Kay

申请号：

AU2011265561

公开号：

AU2011265561A1

申请日:

2011.12.23

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

#$%^&*AU2011265561A120120202.pdf#####C:\NRPorbl\DCC\GRSW7156 I I.DOC-23/12/2011 Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them Abstract The present invention provides a capsule oral dosage form comprising from 5 mgs to 200 mgs of omeprazole, or a salt, hydrate, or prodrug thereof, from 5 mEq to 20 mEq of sodium bicarbonate, from 0.5 wt% to 3 wt% of a lubricant, wherein the lubricant is sodium stearyl fumarate, and from 2 wt% to 8 wt% croscarmellose sodium, wherein upon administration to a subject Tmax of the omeprazole is obtained within about 30 to 75 minutes.

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