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METHODS AND ORAL FORMULATIONS FOR ENZYME REPLACEMENT THERAPY OF HUMAN LYSOSOMAL AND METABOLIC DISEASES
专利权人:
NEW YORK UNIVERSITY
发明人:
Kam-meng TCHOU-WONG,Frank MARTINIUK
申请号:
US14905114
公开号:
US20160346363A1
申请日:
2014.07.14
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The invention provides methods, compositions and kits for enzyme replacement therapy as well as molecular constructs, cells, tissues and plants suitable for expressing recombinant enzymes. Similarly, the invention provides methods for recombinantly producing and orally administering certain metabolic or lysosomal enzymes such as acid alpha glucosidase (GAA) alone, in a pharmaceutical composition or with an activator protein (AGA). Also, the invention provides methods for treating a glycogen storage disease type II (GSDII) or acid maltase deficiency (AMD) or Pompe disease or Fabry disease.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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