University of Pittsburgh—Of the Commonwealth System of Higher Education
发明人:
William F. Goins,Joseph C. Glorioso, III,Justus Bernard Cohen,Bonnie L. Reinhart
申请号:
US15442521
公开号:
US10160959B2
申请日:
2017.02.24
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides a method for ameliorating chronic pain signaling involving transient receptor potential cation channel subfamily V member 1 (TRPV1) by expressing PP1α in neurons. The invention also provides HSV vectors for expressing PP1α within neurons and compositions comprising such vectors.