This invention relates to methods for controlling parasitic infestations ofanimals and their environments, and,more particularly, to methods using isoxazolines to control parasites in or onanimals or in their environments, as well as treatparasitoses of animals. The isoxazolines include 4-(isoxazolinyl)-benzamides(specifically, substituted 4-(5-(halomethyl)-5-phenylisoxazolin-3-yl)-benzamides)and 4-(isoxazolinyl)-benzothioamides (specifically, substituted 4-(5-(halomethyl)-5-phenyl-isoxazolin-3-yl)-benzothioamides).This invention also relates to compositions comprising the isoxazolines foruse in such methods, theuse of the isoxazolines to make medicaments for use in such methods, and kitscomprising the isoxazolines for carrying out suchmethods. This invention further relates to the use of the isoxazolines asmedicaments, particularly medicaments that can be used inthe above-referenced method.