BINDER, JOSEPH JOHN,CHO, HELEN KIM,DERMYER, MICHAEL ROBERT,JOOSS, KARIN UTE,PIERCE, BRIAN GREGORY,TAN, JOYCE TSI,TSAI, VAN TO
申请号:
CA2871711
公开号:
CA2871711A1
申请日:
2013.04.29
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present disclosure provides (a) isolated immunogenic PAA polypeptides; (b) isolated nucleic acid molecules encoding immunogenic PAA polypeptides; (c) vaccine compositions comprising an immunogenic PAA polypeptide or an isolated nucleic acid molecule encoding an immunogenic PAA polypeptide; (d) methods relating to uses of the polypeptides, nucleic acid molecules, and compositions; and (e) vaccine-based immunotherapy regimens which involve co-administration of a vaccine in combination with an immune-suppressive-cell inhibitor and an immune-effector-cell enhancer.