COMPOSITION FOR TREATING OBESITY AND DIABETES AND FOR INCREASING MUSCLE MASS AND IMPROVING CAPACITY FOR EXERCISE, COMPRISING EXTRACTS OF PIPER RETROFRACTUM VAHL. FRUITS AS ACTIVE INGREDIENTS
PROBLEM TO BE SOLVED: To provide a food composition and a pharmaceutical composition, which exhibit anti-obesity effects by means of a thermogenesis produced by an activity of an uncoupling protein (UCP) of fat cells, exhibit anti-diabetes effects by means of an improved insulin resistance, increase muscle mass, and improve capacity for exercise.SOLUTION: There are provided a novel use of a composition containing extracts of piper retrofractum； and a food composition or a pharmaceutical composition which exhibit anti-obesity effects by means of decreased body weight and body fat, exhibit anti-diabetes effects by means of ameliorated insulin resistance through the reduction of blood glucose and blood insulin, increase muscle mass by increasing an energy source being supplied to the muscles, and improve the capacity for exercise including increased endurance. An anti-obese pharmaceutical composition and a food composition which include a Piper retrofractum Vahl. fruit extract, as an active ingredient, obtained with an organic solvent or by supercritical extraction are also provided, where the active ingredient triggers a UCP activation-induced thermogenesis mechanism.SELECTED DRAWING: None【課題】脂肪細胞の脱共役蛋白質（ＵＣＰ）の活性によってもたらされる熱発生によって抗肥満効果を発揮し、向上されたインスリン抵抗性による抗糖尿病効果を発揮し、筋肉量を増大し、運動能力を向上させる食品組成物及び医薬組成物の提供。【解決手段】ヒハツモドキの抽出成分を含む組成物の新規使用、及び、低減された体重及び体脂肪によって抗肥満効果を発揮し、血中グルコース及び血中インスリンの低減による改善されたインスリン抵抗性によって抗糖尿病効果を発揮し、筋肉に供給されるエネルギー源を増大することによって筋肉量を増加し、増大した耐久性を含む運動能力を向上させる食品組成物や医薬組成物。有機溶媒又は超臨界抽出に寄り得られたヒハツモドキ果実の抽出物成分を有効成分として含み、前記有効成分がＵＣＰ活性化誘導熱発生メカニズムをもたらす、抗肥満医薬組成物や食品組成物。【選択図】なし
