A patient positioning device is provided for restraining movement of a body lying over a top surface of a table and includes a rigid support frame extending transversely over the top surface of the table. A cervical-thoracic notch restraint is securely fixed to the upper support surface of the support frame, via a repositionable fastener, to thereby inhibit movement of the cervical-thoracic notch restraint along the longitudinal axis of the table. The repositionable fastener comprises a holding strength per unit of surface area that is sufficient to support the weight of the body on the table when in an inclined position relative to a ground surface. In one example, a head stabilizer is used to inhibit lateral movement of the head. In another example, a lateral stabilizing pillow is used to inhibit torsional movement of the body.