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FOLATE-RECEPTOR TARGETED IMAGING AGENTS
专利权人:
ENDOCYTE; INC.
发明人:
CHRISTOPHER PAUL LEAMON,MATTHEW A PARKER
申请号:
PT10179508
公开号:
PT2260875E
申请日:
2003.05.06
申请国别(地区):
PT
年份:
2014
代理人:
摘要:
The invention provides a use of a compound of the formula wherein V is a folate, wherein the folate is a substrate for receptor-mediated transmembrane transport in vivo, or a folate receptor binding derivative or analog thereof L is a divalent linker R is a side chain of an amino acid M is a cation of a radionuclide n is 1 or 0 and k is 1 or 0 for imaging a population of cells in an animal pre-injected with unlabeled folate. The combination of the compound with unlabeled folate is also provided.
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