GENERAL INCORPORATED ASSOCIATION TSUKUBA GLOBAL INNOVATION PROMOTION AGENCY
发明人:
Yukio Nagasaki,Shinpei Kudo,Yuji Hiramatsu,Hiroaki Sakamoto,Quoc Thang Bui,Binh Long Vong
申请号:
US15566237
公开号:
US10155009B2
申请日:
2016.04.15
申请国别(地区):
US
年份:
2018
代理人:
摘要:
An object of the present invention is to provide a composition that serves as an efficient arginine substrate for inducible NO synthase (iNOS) in tumor. The present invention provides a polyion complex (PIC) of PEG-b-poly(L-Arg) or poly(L-Arg)-b-PEG-b-poly(L-Arg) and a polyanionic polymer, and use thereof.