Chengdu Southwest Jiaotong University Science and Technology Garden Management Co.,Ltd.;Chengdu Jiaoda Medical Science And Technology Company Limited
发明人:
Zhilu YANG,Nan HUANG,Jin WANG,Yajun WENG
申请号：
US15503172
公开号：
US20170246353A1
申请日:
2015.08.12
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Disclosed is a method for preparing a nitric oxide-generating adherent coating, comprising: preparing a buffer solution containing polyphenol compounds, organic selenium or sulfur compounds and soluble copper salts； then contacting a base material with the solution, and washing and drying to obtain a target product. The nitric oxide-generating material prepared by the method can be used for any medical device, such as an intravascular stent, or materials and any complex-shaped base material, and has the capability of scavenging free radicals and catalyzing RSNO to produce nitrogen monoxide, and also has a response function of reduced glutathione (GSH), an antimicrobial function and all the physiological functions possessed by nitrogen monoxide.
