PURPOSE: A composition containing crude saponin fraction derived from Platycodon grandiflorum extract is provided to promote differentiation of osteroblast and to treat bone diseases. CONSTITUTION: A composition for preventing or treating osteoporosis contains crude saponin fraction derived from Platycodon grandiflorum as an active ingredient. The crude saponin fraction is prepared by adsorbing hot water extract of Platycodon grandiflorum onto an ion exchange resin column, removing saccharides using water, eluting adsorbed organic materials using methanol. A functional health food for preventing or treating osteoporosis contains the crude saponin fraction as an active ingredient. The functional health food is manufactured in the form of a drink, sausage, bread, candy, snack, noodle, and ice cream.본 발명은 장생도라지 추출물 유래의 조사포닌 분획물을 유효성분으로 하는 골다공증 예방 및 치료용 조성물에 관한 것으로 상기 조사포닌 분획물은 조골세포의 분화를 촉진하는 효과가 있어 골다공증을 비롯한 골질환의 치료에 효과적이다.
