The present invention provides a patch preparation containing a support and an adhesive layer on at least one surface of the support, wherein the adhesive layer contains a drug, amine oxide, a low-polar liquid component based on an organic compound having an angle of 0 - 19° as calculated by the formula (I): angle ° = arctan �¡ inorganic value / organic value × 180 / À and using an inorganic value and an organic value on an organic conceptual diagram, and an adhesive base, and the adhesive layer has an amine oxide content of 0.1 - 5 wt% and a low-polar liquid component content of 30 - 50 wt%.