Claims relate to an organ care system for maintaining an ex vivo lung in a near physiologic functioning condition comprising:a perfusion circuit for flowing fluid into and out of the ex vivo lung; a composition for use in the perfusion circuit to maintain the ex vivo lung in the near physiologic functioning condition, the composition comprising one or more carbohydrates that include dextran, and a plurality of amino acids that do not include asparagine, glutamine, or cysteine; anda nutritional subsystem comprising an infusion pump.