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Functionalized nanodiamonds as delivery platforms for nucleic acids
专利权人:
University of Saskatchewan
发明人:
Ildiko Badea,Ronald Verrall,Jackson M. Chitanda,Randeep Kaur,Saniya Alwani
申请号:
US14255001
公开号:
US09359282B2
申请日:
2014.04.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present application relates to functionalized nanodiamonds, to complexes comprising a functionalized nanodiamond reversibly bound to a nucleic acid and to compositions comprising such functionalized nanodiamonds and complexes. In particular, the functionalized nanodiamonds comprise at least one naturally occurring basic amino acid, or analogs or derivatives thereof, covalently linked to a nanodiamond. The present application also includes methods and uses of the complexes and compositions, for example for delivering a nucleic acid to a cell.
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