The present invention discloses an atomization device matched up with breathing of user, which includes an atomization module, and a control unit and a conversion unit of exhaling atomization and inhaling atomization. The atomization module includes a nozzle sheet and an oscillation sheet. The control unit of exhaling atomization and inhaling atomization records a high inhaling atomization parameter corresponding to an inhaling time parameter for providing a high inhaling atomization amount, and a low exhaling atomization parameter corresponding to an exhaling time parameter for providing a low inhaling atomization amount. The conversion unit of exhaling atomization and inhaling atomization alternately repeats a high exhaling atomization amount and a low exhaling atomization amount. When the atomization module generates a high inhaling atomization amount, the user inhales the high inhaling atomization amount matched up with the negative pressure formed by inhaling: and when the atomization module generates a low exhaling atomization amount, the user rejects inhaling of the low inhaling atomization amount due to the resistance formed by exhaling, so as to reduce the waste of atomization liquid.本發明揭露種搭配使用者呼吸之霧化裝置,其包含霧化模組、呼氣霧化及吸氣霧化之控制單元、變換單元。霧化模組具有噴孔片及震盪片。呼氣霧化及吸氣霧化之控制單元記錄有吸氣高霧化參數對應吸氣時間參數,以提供高吸氣霧化量,呼氣低霧化參數對應呼氣時間參數,以提供低吸氣霧化量。呼氣霧化及吸氣霧化之變換單元係反覆交錯高呼氣霧化量及低呼氣霧化量。當霧化模組產生高吸氣霧化量時,配合使用者因吸氣形成負壓而吸收高吸氣霧化量,當霧化模組產生低呼氣霧化量時,使用者因呼氣形成阻力而排斥低呼氣霧化量之吸收,以減少霧化液浪費。1‧‧‧搭配使用者呼吸之霧化裝置2‧‧‧霧化模組21‧‧‧高吸氣霧化量22‧‧‧低呼氣霧化量23‧‧‧噴孔片24‧‧‧震盪片3‧‧‧呼氣霧化及吸氣霧化之控制單元31‧‧‧吸氣時間參數32‧‧‧呼氣時間參數33‧‧‧吸氣高霧化參數34‧‧‧呼氣低霧化參數35‧‧‧呼氣霧化及吸氣霧化之變換單元4‧‧‧霧化液51‧‧‧增大噴孔片開口52‧‧‧提高電壓以提高震盪片振幅53‧‧‧增加震盪片震盪頻率54‧‧‧減小噴孔片開口55‧‧‧降低電壓以減低震盪片振幅56‧‧‧減少震盪片震盪頻率