Doris Coit;Angelica Medina-Selby;Philip R. Dormitzer;Ethan Settembre
发明人:
Ethan Settembre,Angelica Medina-Selby,Doris Coit,Philip R. Dormitzer
申请号：
US13808157
公开号：
US20130171185A1
申请日:
2011.07.05
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention relates to chimeric norovirus VP1 proteins containing the S-domain of VP1 of a first norovirus strain and a P-domain that contains at least a portion of the P-domain of VP1 of a second norovirus strain. The invention also relates to nucleic acids that encode the chimeric VP1 proteins, virus-like particles that contain a chimeric norovirus VP1 protein, and to immunogenic compositions.
