UNDERWOOD Mark Y.,UNDERWOOD Mark Y.,MOYER James R.,MOYER James R.
申请号：
SI201231064
公开号：
SI2780027T1
申请日:
2012.11.15
申请国别(地区):
SI
年份:
2017
代理人:
摘要：
The present invention provides apoaequorin-based compositions and methods for preconditioning neurons in a subject to reduce neuronal injury due to brain ischemia. Methods include the step of administering apoaequorin to neurons in a subject, wherein the apoaequorin initiates a change in cytokine expression levels resulting in a reduction of neuronal injury due to brain ischemia as compared to neurons not administered the apoaequorin. Various formulations, including injectable dosages, are described.
