Stable crystal form of tipiracil hydrochloride and crystallization method for the same

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专利权人:

Taiho Pharmaceutical Co.; Ltd.

发明人:

KAZUNO, Hideki,MUTSUMI, Tomonobu

申请号：

AU2017208215

公开号：

AU2017208215A1

申请日:

2017.07.24

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

#$%^&*AU2017208215A120170810.pdf#####31 ABSTRACT An objective of the present invention is to obtain a stable crystal form of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrim idinedione hydrochloride. The present invention provides a crystal of 5-chloro-6-(2-iminopyrrolidin-1-yl)methyl-2,4(1H,3H)-pyrim idinedione hydrochloride exhibiting characteristic peaks at two or more angles selected from the group consisting of 10.5, 19.6, 23.7, 26.2, and 31.2as a diffraction angle (20 ± 0.10) in powder X-ray diffraction.32 Fig. 1 Li i i

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