2-AMINO-4-PHÉNYL-DIHYDROQUINOLÉINES SUBSTITUÉES, PROCÉDÉ DE PRÉPARATION, UTILISATION EN TANT QUE MÉDICAMENT ET MÉDICAMENT LES CONTENANT

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专利权人:

SANOFI

发明人:

LANG, HANS-JOCHEN,WESTON, JOHN,HEINELT, UWE

申请号：

EP07723091.0

公开号：

EP1999112B1

申请日:

2007.03.08

申请国别(地区):

EP

年份:

2015

代理人:

摘要：

The invention relates to NHE-3 inhibitor compounds of formula I: In which R1-R11 are more specifically defined herein. These substituted 2-amino-4-phenyl-dihydroquinolines are useful the treatment of various renal and respiratory disorders such as acute or chronic renal failure, for impairments of biliary function and respiratory impairments such as snoring, sleep apneas or stroke. Formulations comprising them and methods for their use are also described herein.

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