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COMPOSITIONS PHARMACEUTIQUES ET PROCÉDÉS ASSOCIÉS
专利权人:
TYME; INC.
发明人:
HOFFMAN, STEVEN
申请号:
EP13738179
公开号:
EP2804599A4
申请日:
2013.01.16
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The invention relates to a pharmaceutical composition comprising: a tyrosine hydroxylase inhibitor; and melanin, a melanin promoter, or a combination thereof. The invention also relates to a tyrosine hydroxylase inhibitor that is a-methyl-DL-tyrosine for use in treating cancer. Pharmaceutical compositions and kits including a tyrosine hydroxylase inhibitor; melanin, a melanin promoter, or a combination thereof; a p450 3A4 promoter; and a leucine aminopeptidase inhibitor are also provided. Also provided is the treatment of cancer in a subject, comprising administering an effective amount of a tyrosine hydroxylase inhibitor, a melanin promoter, a p450 3A4 promoter, and a leucine aminopeptidase inhibitor to the subject in need thereof. Also provided are means of reducing cell proliferation in a subject comprising administering an effective amount of a tyrosine hydroxylase inhibitor, a melanin promoter, a p450 3A4 promoter, and a leucine aminopeptidase inhibitor to the subject in need thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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