Antibody Fc variants

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专利权人:

Manfred Kubbies;Ekkehard Moessner;Monika Baehner;Stefan Jenewein;Tilman Schlothauer

发明人:

Monika Baehner,Stefan Jenewein,Manfred Kubbies,Ekkehard Moessner,Tilman Schlothauer

申请号：

US13431489

公开号：

US08969526B2

申请日:

2012.03.27

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The invention relates to engineered polypeptides comprising Fc variants and their uses. More specifically, Fc variants are described exhibiting reduced effector function. These variants cause a benefit for a patient suffering from a disease which could be treated with an antibody for which it is desirable to reduce the effector function elicited by antibodies.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/