COMPER, Wayne,RAMACHANDRAN, Aparna,YAN, Haoheng,RUSSO, Leileata, M.,SKOG, Johan Karl Olov
申请号:
HK16105052.6
公开号:
HK1217088A
申请日:
2016.05.04
申请国别(地区):
HK
年份:
2016
代理人:
摘要:
The present invention discloses methods for diagnosing or prognosing a disease or medical condition in a subject by detecting the presence or absence of BRAF mutant nucleic acids from nucleic acids extracted from microvesicles from a biological sample. The present invention also discloses methods for assessing the responsiveness or determining a treatment regimen for a subject in need thereof by detecting the presence or absence of BRAF mutant nucleic acids from nucleic acids extracted from microvesicles from a biological sample. Methods for isolating microvesicles and extracting DNA and/or RNA from the microvesicles are also described.