Vaccines are provided comprising a recombinant virus which expresses an immunomodulatory protein and a target antigen unrelated to said recombinant virus, and a pharmaceutically acceptable excipient.L'invention concerne des vaccins comprenant un virus recombinant qui exprime une protéine immunomodulatrice et un antigène cible non lié audit virus recombinant, ainsi qu'un excipient pharmaceutiquement acceptable.