Daniel G. Stearns,Bradley W. Rice,Michael D. Cable
申请号：
US12947794
公开号：
US08909326B2
申请日:
2010.11.16
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides systems and methods for obtaining a three-dimensional (3D) representation of one or more light sources inside a sample, such as a mammal. Mammalian tissue is a turbid medium, meaning that photons are both absorbed and scattered as they propagate through tissue. In the case where scattering is large compared with absorption, such as red to near-infrared light passing through tissue, the transport of light within the sample is described by diffusion theory. Using imaging data and computer-implemented photon diffusion models, embodiments of the present invention produce a 3D representation of the light sources inside a sample, such as a 3D location, size, and brightness of such light sources.
