Nitzel, Gregory Paul,Ankenbauer, Robert Gerard,Calvert, Jay Gregory,Dunyak, Donna Steuerwald,Marx, Jacqueline Gayle,Oien, Nancee Lois,Pearce, Douglas Steven,Stoeva, Mira Ivanova,Thompson, James Richar
申请号：
AU2009303845
公开号：
AU2009303845B2
申请日:
2009.10.16
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
The present invention is directed to novel nucleotide and amino acid sequences of Torque teno virus ("TTV"), including novel genotypes thereof, all of which are useful in the preparation of vaccines for treating and preventing diseases in swine and other animals. Vaccines provided according to the practice of the invention are effective against multiple swine TTV genotypes and isolates. Diagnostic and therapeutic polyclonal and monoclonal antibodies are also a feature of the present invention, as are infectious clones useful in the propagation of the virus and in the preparation of vaccines. Particularly important aspects of the invention include vaccines that provide TTV ORF1 protein, or peptide fragments thereof, as antigen.
