COMBINATION OF CATALYTIC MTORC1/2 INHIBITORS AND SELECTIVE INHIBITORS OF AURORA A KINASE

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专利权人:

MILLENNIUM PHARMACEUTICALS; INC.

发明人:

BRAKE, RACHEL,NIU, HUIFENG

申请号：

CA2907726

公开号：

CA2907726A1

申请日:

2014.03.21

申请国别(地区):

CA

年份:

2014

代理人:

摘要：

Disclosed are methods for the treatment of proliferative disorders. Disclosed in particular, are methods for treatment of proliferative disorders such as cancer, by administering an mTORC1/2 inhibitor in combination with a selective inhibitor of Aurora A kinase. Preferred MTORC1/2 inhibitors include MLN0128 and the preferred Aurora A kinase inhibitor of the combination is MLN8237.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/