The present invention provides agents having inhibiting function for kidney glomerular diseases and kidney arteriosclerosis, agents for preventing renal failure, and functional foods promising effects for preventing renal failure. The inhibitor agent for kidney glomerular diseases and kidney arteriosclerosis of the present invention contains Xaa Pro Pro as an effective component.依據本發明而提供具有抑制腎臟絲球體疾病及腎動脈硬化之作用的藥劑、以及含有上述藥劑之腎衰竭預防劑與可期待預防腎衰竭之效果的功能性食品。本發明之腎臟絲球體疾病以及腎動脈硬化之抑制劑係包含Xaa Pro Pro作為有效成分。
