Jonathan Robert Barclay Dupere,Liesbeth de Jong,Edwin J. Wagena
申请号：
US15688555
公开号：
US20180055884A1
申请日:
2017.08.28
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention refers to a cell suspension of autologous or allogeneic, preferably autologous, adult bone marrow-derived white blood cells, preferably derived from the crest of the ilium (or iliac crest), enriched for mononuclear cells, meaning more than 25% of the white blood cells (WBCs) present in the cell suspension are mononuclear cells, and comprising:A. Mononuclear cells (MNC) selected from the list comprising or consisting of: i. A population of Lymphocytesii. A population of Monocytes andiii. A population of Hematopoietic stem cells expressing CD34and wherein the cell suspension further comprises:B. Granulocytesfor use in the treatment or amelioration of lower extremity peripheral artery disease.
