THOMPSON, PETER ARMSTRONG,ODEGARD, VALERIE,DUBOSE, ROBERT FINLEY,SMITH, SEAN WESLEY,COBURN, CRAIG ALAN
申请号:
CA3084667
公开号:
CA3084667A1
申请日:
2018.12.14
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
Various compositions are disclosed for the treatment of viral infections. The compositions comprise antibody constructs directed to the liver, attached to myeloid cell agonists, specifically TLR7 and TLR8 agonists, via a linker. Additionally provided are the methods of preparation and use of the conjugates. This includes methods for treating viral infections, such as viral liver diseases.