Dennis D. Jamiolkowski,Daniel Steiger,Brian M. Kelly,Christopher DeFelice,Sasa Andjelic,Modesto Erneta
申请号:
US14548536
公开号:
US20150148496A1
申请日:
2014.11.20
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Novel absorbable polymeric blends are disclosed. The blends have a first absorbable polymer type that is a polylactide polymer or a copolymer of lactide and glycolide and a second absorbable polymer type that is poly(p-dioxanone), wherein the first absorbable polymer type or the second absorbable polymer type or the first absorbable polymer type and the second absorbable polymer type additionally comprise a first polymeric component and a second polymeric component. The first polymeric component has a higher weight average molecular weight than the second polymeric component and at least one of said components is at least partially end-capped by a carboxylic acid. The novel polymeric blends are useful for manufacturing medical devices having dimensional stability, having engineered degradation and breaking strength retention in vivo. Also disclosed are novel absorbable medical devices made from these novel polymer blends, as well as novel methods of manufacture.