Chimeryczny receptor antygenowy (CAR) anty-CD123 do zastosowania w leczeniu nowotworu złośliwego

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专利权人:

Novartis AG;The Trustees Of The University Of Pennsylvania

发明人:

KENDERIAN, SAAD,BROGDON, JENNIFER,GILL, SAAR,GLASS, DAVID,LOEW, ANDREAS,MANNICK, JOAN,MILONE, MICHAEL,MURPHY, LEON,PORTER, DAVID L.,RUELLA, MARCO,WANG, YONGQIANG,WU, QILONG,ZHANG, JIQUAN

申请号：

PL15756525

公开号：

PL3183268T3

申请日:

2015.08.19

申请国别(地区):

PL

年份:

2020

代理人:

摘要：

The invention provides compositions and methods for treating diseases associated with expression of CD123. The invention also relates to chimeric antigen receptor (CAR) specific to CD123, vectors encoding the same, and recombinant cells comprising the CD123 CAR. The invention also includes methods of administering a genetically modified cell expressing a CAR that comprises a CD123 binding domain.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/