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Cartilage repair methods
专利权人:
Mitchell S. Seyedin
发明人:
Mitchell S. Seyedin,Matthew Matava
申请号:
US11635265
公开号:
US08444968B2
申请日:
2006.12.07
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present application discloses methods for repairing hyaline cartilage defects. The methods comprise a combination of introducing autologous bone mesenchymal stem cells to a joint, and applying to the joint a membrane comprising a polyester entangled with a polysaccharide. In some aspects, the bone mesenchymal stem cells are mesenchymal stem cells originating in bone underlying the joint. In these aspects, contact between the joint and the mesenchymal stem cells can be effected by introducing apertures through the bone using standard surgical techniques such as microfracture, abrasion, or drilling. Cartilage which forms in response to application of these methods is hyaline cartilage rather than fibrocartilage.
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