QUINOLINE CONTAINING COMPOUNDS AND THEIR USE FOR TREATING ENDOPLASMIC RETICULUM STRESS-RELATED DISEASES

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专利权人:

Russell Dahl

发明人:

Russell Dahl

申请号：

US15361485

公开号：

US20170231973A1

申请日:

2016.11.27

申请国别(地区):

US

年份:

2017

代理人:

摘要：

Provided herein are quinoline, pharmaceutical compositions thereof, and methods of their use for treating, preventing, or ameliorating one or more symptoms of an endoplasmic reticulum stress-caused disease. Also provided herein are methods of their use for reducing endoplasmic reticulum stress and modulating the activity of a sarcoplasmic/endoplasmic reticulum Ca2+ATPase.

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