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MEANS FOR PREVENTIVE AND / OR THERAPEUTIC TREATMENT OF PERIPHERAL NEUROPATHIC PAIN CAUSED BY ANTI-CANCER
专利权人:
АСАХИ КАСЕИ ФАРМА КОРПОРЕЙШН (JP);КИНКИ ЮНИВЕРСИТИ (JP)
发明人:
КАВАБАТА Ацуфуми (JP),СУЗУКИ Хидеаки (JP)
申请号:
RU2014148171
公开号:
RU2014148171A
申请日:
2013.05.17
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A drug for the prophylactic and / or therapeutic treatment of peripheral neuropathic pain induced by chemotherapy, containing thrombomodulin as an active ingredient. The medicament according to claim 1, wherein thrombomodulin is a soluble thrombomodulin. The medicament according to claim 1 or 2, wherein thrombomodulin is human thrombomodulin. The medicament according to claim 1 or 2, wherein the peripheral neuropathic pain is one or more types of symptoms selected from numbness of the extremities, pain in the extremities, decreased deep reflexes of tendons, decreased muscle strength, allodynia, hyperalgesia and motor dysfunction. 5. The medicament according to claim 1 or 2, wherein the peripheral neuropathic pain is allodynia. The medicament according to claim 5, wherein allodynia is mechanical allodynia. A drug according to claim 1 or 2, wherein the anticancer drug during chemotherapy consists of one or more types of drugs selected from the group consisting of taxane drugs and a platinum preparation. The medicament according to claim 1, wherein the anticancer agent during chemotherapy is paclitaxel. The medicament according to claim 1, wherein the anticancer agent during chemotherapy is administered in accordance with FOLFOX therapy or FOLFIRI therapy. The medicament according to claim 1 or 2, wherein thrombomodulin is administered periodically. The medicament according to claim 1, which is administered to a patient with a malignant neoplasm suffering from one or more types of malignant neoplasms selected from the group consisting of ovarian cancer, non-small cell lung cancer, milk jelly cancer1. Лекарственное средство для профилактического и/или терапевтического лечения периферической нейропатической боли, индуцируемой химиотерапией, содержащее тромбомодулин в качестве активного ингредиента.2. Лекарственное средство по п. 1, где тромбомодулин является растворимым тромбомодулином.3. Лекарственное средство по п. 1 или 2, где тромбомодулин является тромбомодулином
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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