The invention discloses the compositions and preparation that are handled with what clean or infection wound, some in invention formulation can be reduced or eliminated with what such as the microbial contamination of skin and lifeless object (for example, table top, mess kit, Medical Devices, cooker, food, scrub auxiliary agent and agriculture biocide) surface. Some in these compositions and preparation are very suitable to what wound dressing. Some growths that can kill and/or inhibit pathogenic bacteria, fungi, gemma and virus in the preparation. The preparation generates the compound of the high concentration osmoticum of osmotic gradient and at least one integrality for destroying microbial film or cell wall including, for example, being enough. These preparations are optionally including at least one reagent for making the preparation thickening. In certain aspects, the preparation is the form of emulsion.本發明公開了用於對清潔的或感染的傷口進行處理的組合物和製劑,本發明製劑中的一些可以用於减少或消除例如皮膚和無生命物體(例如,檯面、烹調用具、醫療設備、炊具、食品、刷洗助劑和農業殺生物劑等)表面的微生物污染。這些組合物和製劑中的一些非常適合用於傷口敷料。所述製劑中的一些能够殺傷和/或抑制致病細菌、真菌、芽孢和病毒的生長。所述製劑包含例如足以産生滲透梯度的高濃度滲壓劑以及至少一種破壞微生物膜或細胞壁之完整性的化合物。這些製劑可任選地包含至少一種使所述製劑增稠的試劑。在一些方面中,所述製劑是乳劑的形式。