METHODS AND COMPOSITIONS FOR NANOPARTICLE-MEDIATED CANCER CELL-TARGETED DELIVERY

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专利权人:

发明人:

申请号：

EP11733532.3

公开号：

EP2525835A2

申请日:

2011.01.18

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The present invention provides methods and compositions to selectively and directly deliver nanoparticles carrying an active agent to tumor cells. The active agent is internalized by the tumor cells, producing an anti-tumor effect for therapeutic applications and/or depositing a detectable marker for diagnostic applications. The present invention further provides a p53 chimera that circumvents the dominant negative activity of mutant p53 as a therapeutic in the treatment of cancer and reduction of mor size.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/