Darrow, James W.,Xu, Jianjun,Currie, Kevin S.,Lee, Seung H.,Mitchell, Scott A.,Schmitt, Aaron C.,Kropf, Jeffrey E.,Blomgren, Peter A.
申请号：
AU2007296559
公开号：
AU2007296559B2
申请日:
2007.09.11
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
At least one chemical entity chosen from compounds of Formula (1) and pharmaceutically acceptablesalts, solvates, chelates, non-covalent complexes, prodrugs, and mixturesthereof is described herein. Pharmaceutical compositions comprising at leastone chemical entity of the invention, together with at least one pharmaceutically acceptablevehicle chosen from carriers adjuvants, and excipients, are described. Methodsof treating patients suffering from certain diseases responsive to inhibitionof Btk activity and/ or B-cell activity are described. Methods for determiningthe presence of Btk in a sample are described.
