An apparatus and method for indicating treatment site locations for phototherapy to the brain are disclosed. In some embodiments, the apparatus is a headpiece wearable by a patient. The headpiece includes a body adapted to be worn over at least a portion of the patient's scalp and a plurality of position indicators corresponding to a plurality of treatment site locations at the patient's scalp where a light source is to be sequentially positioned such that light from the light source is sequentially applied to irradiate at least a portion of the patient's brain. At least one of the position indicators includes an optically transmissive portion having an area of at least 1 cm2 through which the light propagates.