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TREATING DISEASES MEDIATED BY BLOCKADE OF THE EPITHELIAL SODIUM CHANNEL WITH PYRAZINE-2-CARBOXAMIDE DERIVATIVES
专利权人:
Paul OAKLEY;Nichola SMITH;Peter GEDECK;Thomas Anthony HUNT;Gurdip BHALAY;Graham Charles BLOOMFIELD;Catherine HOWSHAM;Lee EDWARDS;Andrew DUNSTAN;Emma BUDD;Stephen Paul COLLINGWOOD;Peter HUNT
发明人:
Gurdip BHALAY,Emma BUDD,Graham Charles BLOOMFIELD,Stephen Paul COLLINGWOOD,Andrew DUNSTAN,Lee EDWARDS,Peter GEDECK,Catherine HOWSHAM,Peter HUNT,Thomas Anthony HUNT,Paul OAKLEY,Nichola SMITH
申请号:
US14847262
公开号:
US20160068546A1
申请日:
2015.09.08
申请国别(地区):
US
年份:
2016
代理人:
摘要:
A compound of Formula Iin free or salt or solvate form, where R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
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来源网址:
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