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Absorbent crosslinked form stable membrane
专利权人:
가이스틀리히 파마 아게
发明人:
슈티펠 니클라우스,슈텐첼 세르게이,카우프만 라파엘
申请号:
KR1020187015487
公开号:
KR1019189080000B1
申请日:
2016.12.02
申请国别(地区):
KR
年份:
2018
代理人:
摘要:
The present invention relates to the following: An absorbent, crosslinked, shape-stable membrane for oral use, comprising: a collagen material comprising 1.5 to 3.5 parts by weight of inorganic ceramic with respect to 1 part by weight of collagen material sandwiched between two layers of elastomeric pretensted collagen material; An absorbable crosslinked form stable membrane comprising a composite layer of inorganic ceramic particles, wherein the collagen material comprises 50-100% (w / w) collagen and 0-50% (w / w) elastin, The absorbable, crosslinked, form-stable membrane as an implant for use in assisting bone formation, bone regeneration, bone resorption and / or bone replacement at a deficient tooth bone defect site in a human or animal, - a process for producing said absorbent crosslinked, form stable membrane, comprising the steps of: (a) preparing a composite layer of a collagen material and inorganic ceramic particles, optionally crosslinking said composite layer, (b) a composite layer of a collagen material and inorganic ceramic particles is assembled and adhered between two layers of a collagen material which is stretched to induce elongation of the collagen material in a linear region of a stress-strain curve, and elastic pretension collagen Obtaining a composite layer of inorganic ceramic particles and collagen material sandwiched between two layers of material, and (c) crosslinking the composite layer of the inorganic ceramic particles and the collagen material sandwiched between the two layers of the elastic pretilt collagen material, and then applying a hydrophilic treatment thereto.본 발명은, 하기에 관한 것이다:- 구강 내 사용을 위한 흡수성의 가교된 형태 안정적 멤브레인으로서, 탄성 프리텐스트 콜라겐 재료의 2 개의 층 사이에 샌드위치된, 1 중량부의 콜라겐 재료에 대하여 1.5 내지 3.5 중량부의 무기 세라믹을 함유하는 콜라겐 재료와 무기 세라믹 입자의 복합체 층을 포함하고, 콜라겐 재료가 50-100 % (w/w) 콜라겐 및 0-50 % (w/w) 엘라스틴을 포함하는 흡수성의 가교된 형태 안정적 멤브레인,- 인간 또는 동물의 결손된 치아 뼈 결함 부위에서 뼈 형성, 뼈 재생, 뼈 복원 및/또는 뼈 대체를 보조하는데 사용하기 위한 임플란트로서의, 상기 흡수성의 가교된 형태 안정적 멤브레인, - 하기의 단계를 포함하는,
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