Polyvinyl chloride polyvinyl chloride-pyrophosphate-phosphoric acid-1 (NPP1) polyvinyl chloride, including Catalan control of NPP1 endpoint, FC region of immunoglobulin, alternative directions； coded nucleic acid； vector； Huesped cells.

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专利权人:

SYNAGEVA BIOPHARMA CORP.

发明人:

QUINN, ANTHONY,HARVEY, ALEX J.,XIA, ZHINAN

申请号：

CL2013002607

公开号：

CL2013002607A1

申请日:

2013.09.10

申请国别(地区):

CL

年份:

2014

代理人:

摘要：

The present invention provides a novel fusion polypeptide containing a catalytic portion of NPP1 fused to a targeting moiety, nucleic acids encoding the fusion polypeptide, a vector containing the nucleic acid integrated thereinto, a host cell transformed with the vector and pharmaceutical compositions comprising the fusion polypeptide.POLIPEPTIDO DE FUSION NUCLEOTIDO PIROFOSFATASA/FOSFODIESTERASA 1 (NPP1) QUE COMPRENDE UN DOMINIO CATALITICO DEL EXTREMO C-TERMINAL DE NPP1, UNA REGIÓN FC DE UNA INMUNOGLOBULINA Y OPCIONALMENTE UN RESTO DE DIRECCIONAMIENTO； ÁCIDO NUCLEICO QUE LO CODIFICA； VECTOR； CELULA HUESPED.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/