ZAGER, RICHARD A.,OLSON, JAMES M.,GIRARD, EMILY J.,CORRENTI, COLIN E.,SOTTERO, THEO L.
申请号：
CA3005928
公开号：
CA3005928A1
申请日:
2016.12.09
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
The present disclosure provides compositions and methods for renal therapy. In various aspects, the present disclosure provides a composition comprising a knotted peptide, wherein upon administration to a subject the knotted peptide homes, targets, is directed to, accumulates in, migrates to, is retained by, and/or binds to renal tissue of the subject. In various aspects, the composition further comprises an active agent coupled to the knotted peptide. The composition, when administered to the subject, may induce protective preconditioning or acquired cytoresistance.
