The invention relates to 3-(carboxymethyl)-8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives, their preparation and their use in medicine, particularly in the treatment of pain.本發明係關於3-(羧甲基)-8-胺基-2-側氧基-1,3-二氮-螺-[4.5]-癸烷衍生物、其等之製備以及其等於醫學(特別係於治療疼痛)之用途。