MEMORIAL SLOAN KETTERING CANCER RESEARCH;CORNELL UNIVERSITY
发明人:
YOO, BARNEY,BRADBURY, MICHELLE S.,WIESNER, ULRICH,MA, KAI
申请号：
CA2947895
公开号：
CA2947895A1
申请日:
2015.05.27
申请国别(地区):
CA
年份:
2015
代理人:
摘要：
Described herein are nanoparticle drug conjugates (NDCs), which, in certain embodiments, comprise a non-toxic, multi-modality, clinically proven silica-based nanoparticle platform with covalently attached drug molecules/moieties. The nanoparticle drug conjugates (NDCs) demonstrate imaging capability and targeting ligands which efficiently clear through the kidneys. Furthermore, the conjugates incorporate therapeutic agents for cancer detection, prevention, and/or treatment.
