Described is a method of producing mammalian ADH in plants and a method of producing mammalian ALDH in plants. The ADH and ALDH is preferably of human origin and preferably human class IV sigma ADH and human ALDH2. Mammalian ADH and ALDH is recovered from the plants and packaged with NAD and a suitable buffer as a pill, paste, or food snack. The composition is taken orally or otherwise before engaging in social drinking to prevent or ameliorate the effects of alcohol consumption.