Robert L. Hudkins;Ming Tao;Kurt A. Josef;Derek Dunn;Nadine C. Becknell;Lars J. S. Knutsen;Allison L. Zulli
发明人:
Nadine C. Becknell,Derek Dunn,Robert L. Hudkins,Kurt A. Josef,Lars J. S. Knutsen,Ming Tao,Allison L. Zulli
申请号:
US12815800
公开号:
US08207168B2
申请日:
2010.06.15
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention is directed to novel pyridazinone derivatives that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of the histamine H3 receptor, including, for example, neurodegenerative disorders, sleep/wake disorders, attention deficit hyperactivity disorder and cognition disorders.