SALT OF FUSED HETEROCYCLIC DERIVATIVE AND CRYSTAL THEREOF
- 专利权人:
- 깃세이 야쿠힌 고교 가부시키가이샤
- 发明人:
- 조 카즈미치,타케우치 히데키
- 申请号：
- KR1020127021797
- 公开号：
- KR1016311430000B1
- 申请日:
- 2011.02.09
- 申请国别(地区):
- KR
- 年份:
- 2016
- 代理人:
- 摘要：
- The present invention relates to a process for the preparation of 3- [2-fluoro-5- (2,3-difluoro-6-methoxybenzyloxy) -4- methoxyphenyl] 4-tetrahydrothieno [3,4-d] pyrimidine-5-carboxylic acid is improved. The present invention provides a choline salt of formula (A) having excellent solubility and storage stability.본 발명은 3-[2-플루오로-5-(2,3-디플루오로-6-메톡시벤질옥시)-4-메톡시페닐]-2,4-디옥소-1,2,3,4-테트라히드로티에노[3,4-d]피리미딘-5-카르복실산의 용해성을 개량하는 것을 과제로 한다. 본 발명은 우수한 용해성 및 보존안정성을 갖는 식 (A)의 콜린염을 제공한다.
- 来源网站：
- 中国工程科技知识中心
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