The present invention relates to a multilamella nanoliposome which is biocompatible and in which a ceramide, a peptide derived from a living body, and hyaluronic acid are stably collected. The present invention provides a multilamella nanoliposome and a preparation method therefor, the multilamella nanoliposome being suitable for a cosmetic composition for overall skin improvements such as skin moisturizing enhancement, skin aging prevention, skin wrinkle improvement, etc. due to having excellent skin absorptivity and permeability.La présente invention concerne un nanoliposome multilamellaire biocompatible et dans lequel un céramide, un peptide dérivé dun corps vivant et de lacide hyaluronique sont recueillis de manière stable. La présente invention concerne un nanoliposome multilamellaire et son procédé de préparation, le nanoliposome multilamellaire étant approprié pour une composition cosmétique visant à une amélioration de la peau de manière générale, telle que lamélioration de lhydratation de la peau, la prévention du vieillissement de la peau, latténuation des rides, etc. grâce à dexcellentes capacités dabsorption et de perméabilité cutanées.본 발명은 생체친화적이고 세라마이드, 생체유래 펩타이드 및 히알루론산이 안정적으로 포집되어 있는 나노 다층 리포좀에 관한 것으로, 피부 흡수 및 투과성이 뛰어나 피부 보습력 향상, 피부 노화 방지, 피부 주름 개선 등 전반적인 피부 개선을 위한 화장료 조성물에 적합한 나노 다층 리포좀 및 이의 제조방법을 제공한다.